Clinical Trials

Tetranite Vet is a novel bone adhesive that is transforming the standard of care for both patients and veterinary clinicians. We are currently enrolling patients and conducting a range of studies in 5 cities around the country with a team of experienced investigators. 
If you are interested in having your family pet participate in any of the current or future trials, please see the information below.  

CLINICAL STUDIES

RevBio Animal Health is currently conducting a multi-center study evaluating the rate of bone healing using a novel mineral-organic adhesive (Tetranite Vet) in tooth extraction sites in dogs.

This study is investigating a novel resorbable adhesive bone graft that may not only result in quicker bone healing at tooth extraction sites–but may also maintain ridge height preservation (jaw thickness). Our team is investigating how expedited healing may provide the benefit of helping to maintain the supporting jawbone. We believe delaying alveolar ridge atrophy will help preserve surrounding teeth.

FOR PET PARENTS

To participate in this study, your dog must require a medically necessary extraction of a single large tooth or similar size teeth in the lower jaw. The complete study consists of three visits: An initial visit for the extraction, a short-term follow up at either 6, 8 or 12 weeks and finally a long-term follow-up visit at 6 or 12 months.

Please review some common symptoms which indicate that your dog may require dental care: bad breath, changes in eating habits, yellow or brown teeth, swollen or bleeding gums, growths on the gums, excessive drooling, pawing at their mouth. A veterinarian will provide a diagnosis for suitability. Please see patient incentives below:

INCENTIVE #1$1500 for complete trial participation–$500 for each of three visits.
INCENTIVE #2Placement of resorbable bone adhesive at no cost to the patient.
INCENTIVE #3Immediate post-operative and two follow-up CT scans at no cost.
INCENTIVE #4Anesthesia or sedation costs associated with the CT scans are at no cost.
FOR REFERRING VETERINARIANS

If you have a canine patient who might qualify for this study, please refer the client to one of the investigators. Please see inclusion criteria below:

CRITERIA #1Canine patients having two similar sized teeth in the mandible or matching alveoli in two-rooted mandibular teeth which are recommended to be extracted following a standard anesthetized oral exam and intra oral radiographic evaluation.
CRITERIA #2Canine patients must be older than 1 year of age.
CRITERIA #3Canine patients must tolerate general anesthesia or sedation while undergoing procedures.
CRITERIA #4If enrolled, patient parents must be willing to bring the canine back for a follow-up visit (6, 8, OR
12 weeks) with CT scan and an optional second follow-up visit (12 months) with CT scan.
CLINICAL SITES

RevBio Animal Health clinical studies are being performed in Madison, WI; Salem , CT; Denver, Co; Aurora, IL; Leesburg, VA; Mathews, NC; Lenexa, KS; Norwalk IA and Algodones, NM. See below for more detailed site locations and clinician contact information:

LEAD INVESTIGATOR:

CHRIS SNYDER: DVM, DAVDC
UW VETERINARY CARE
University of Wisconsin School of Veterinary Medicine
2015 Linden Drive
Madison, WI 53706
Office Number: (608) 263-7600
https://uwveterinarycare.wisc.edu

ADDITIONAL INVESTIGATORS:
  • STEPHEN JURIGA: DVM, DAVDC
    Veterinary Dental Center
    345 Sullivan Road
    Aurora, IL 60506
    Office Number: (630) 682-5578
    https://www.veterinarydentalcenter.com
  • Mary Buelow: DVM, DAVDC
    Animal Dentistry & Oral Surgery
    165 Fort Evans Road, NE #106
    Leesburg, VA 20176
    Office Number: (571) 319-8169
    https://animaldentalspecialist.com
  • Scott MacGee: DVM, DAVDC
    Companion Animal Dentistry
    14918 W. 87th Street
    Lenexa, KS 66215
    Office Number: (913) 742-8686
    http://kcpetdental.com
  • Susan E. Crowder: DVM, DAVDC
    COMPANION ANIMAL DENTISTRY
    14918 W. 87th Street
    Lenexa, KS 66215
    Office Number: (913) 742-8686
    http://kcpetdental.com
  • Kris Bannon: DVM, FAVD, DAVDC
    Veterinary Dentistry & Oral Surgery of NM
    5 Camino Karsten
    Algodones, NM 87001
    Office Number: (505) 471-0747
    https://vetdentistrynm.com
  • KATHERINE QUECK: DVM, FAVD, DAVDC
    Veterinary Dentistry & Oral Surgery
    2440 Plantation Center Dr,
    Matthews, NC 28105
    Office Number: (704) 817-9896
    https://www.hvdos.com/
  • Donald E. Beebe: DVM, DAVDC
    Apex Dog and Cat Dentistry
    945 W. Jefferson Ave.
    Englewood, CO 80110
    Office Number: (303) 810-6029
    https://dentistvet.com
  • JENNIFER MATHIS: DVM, CVPP
    Animal Dentistry Referral Services
    1326 Sunset Drive
    Norwalk, IA 50211
    Office Number: (515) 981-0317
    www.tooth.vet
  • ROBERT M. BARATT: DVM, MS, FAVD, DAVDC
    SALEM VALLEY VETERINARY CLINIC
    12 Centre Street
    Salem, CT 06420
    Office Number: (860) 859-3781
    https://www.salemvalleyvet.com
  • JORDAN W. PETERS: DVM
    SALEM VALLEY VETERINARY CLINIC
    12 Centre Street
    Salem, CT 06420
    Office Number: (860) 859-3781
    https://www.salemvalleyvet.com

If you think your dog may be a candidate for our clinical trials please contact us:

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